According to the studies included in this review, 36 variants in 24 genes (XPG, XPF, XPD, THADA, SUN2, PTEN, PRKCI, PPARG, PCA3, NF-κB1, MTRR, miR-143/miR-145, MEG3, K-ras, KLK3, IL-8, COX-1, CBS, AR gene, AKT2, AKT1, ADIPOQ, GEMIN4, RNASEL) and 2 unmapped SNPs failed to show association with PCa while other polymorphisms had a negative or positive effect (Table 2). The gene discussed is MTRR; the disease is posterior cortical atrophy.