Regarding the increased risks of PCa, among the genes identified above, 29 of 40 polymorphisms in the 20 genes (ZMIZ1, XRCC1, TEX15, SRD5A2, Raptor, RAD23B/ KLF4, RAD17, OR2A5, MTR, MLH3, LILRA3, IL-4, COX-2, Hsa-miR-23a, GATA2, GAS5, FOXP4, C2orf43, EXO1, BIRC5) and 5 unmapped SNPs (rs12653946C > T, rs9600079 G > T, rs1447295 C > A, rs7837328 G > A, rs10505474 G > A) were shown to increase PCa risk in Chinese population, conferring odds ratio (OR) ranged from 1.28–6.68 [16, 18–22, 24, 26–29, 31–35, 37, 40–42, 44, 47, 48]. The gene discussed is MTR; the disease is posterior cortical atrophy.