On the other hand, 7 other SNPs (Raptor rs1468033 G > A, PRKCI rs4955720 C > A, MTHFR rs1801131 C > A, AKT2 rs7250897 T > C, ADIPOQ rs266729 C > G, rs182052 G > A, miR-143/miR-145 rs4705342 T > C) were shown to be not associated with the overall risk of PCa but had positive or negative effects in smokers/non-smokers, High/Low BMI, older/younger subjects, ever drinking, and Uygur ethnicity. This evidence concerns the gene MTHFR and posterior cortical atrophy.