Regarding the disease stage of PCa, subgroups of localized diseased, 3 SNPs in 3 genes (EXO1, IL6, RAD17) were reported to increase risk of PCa (OR = 1.66–3.08, highest: EXO1 C > T) [23, 34, 47], while mTOR rs2295080 T > G decreased the risk. This evidence concerns the gene IL6 and posterior cortical atrophy.