A total of 24 SNPs in 16 genes (EXO1, IL6, mTOR, RAD17, CYR61 (IGFBP10), Vavs, MTHFR, MTR, GAS5, PCA3, PRKCI, DNMT1, DNMT3B, XPC, BIRC5, KLK3) were reported to be associated with the overall disease stage (e.g. localized or advanced disease), Gleason score(high/low), PSA levels, PCa risk, clinicopathological characteristics (e.g. seminal vesicle invasion, positive surgical margin, lymph node involvement, extracapsular extension, aggressive disease) in Chinese with PCa (Supplementary Table 4). Here, MTR is linked to posterior cortical atrophy.