The composition of Type 1 (T‐bet+), Type 2 (GATA3+), Type 17 (RORγT+), NKT‐like (CD56+), regulatory (FOXP3+), follicular (BCL6+), and cytotoxic (CD3+CD8+) or helper (CD3+CD4+) T cells showed marked differences between MSI and MSS patients. This evidence concerns the gene NCAM1 and Marinesco-Sjogren syndrome.