Significant loci revealed by ONT EWAS included CpGs associated with SEPTIN9, a tumour suppressor gene33; TERF2, a telomeric protein linked to tumour formation and progression34; and CNTNAP2, a potential marker of tumour aggressiveness in oligodendrogliomas35, which is also implicated in neurodevelopmental disorders. The gene discussed is TERF2; the disease is neurodevelopmental disorder.