Parallel interrogation of independent MPM patient cohorts (GSE2549 [35], GSE29211 [36], GSE42977 [37], and GSE163722 [38]) corroborated the enrichment of proliferation and cell cycle-related gene sets in tumors with elevated BUB1 levels (Fig. S6A–C), implying that high BUB1 expression promotes tumor cell proliferation in vivo. The gene discussed is BUB1; the disease is neoplasm.