Coimmunoprecipitation (Co-IP) revealed that the antibody against VEGFR2 was able to pull down STAT3 in GBM cells, and the antibody against STAT3 could also pull down VEGFR2, confirming direct binding between VEGFR2 and STAT3 (Fig. 4G). The gene discussed is KDR; the disease is glioblastoma.