FUS and amyotrophic lateral sclerosis: Loss of the autophagy adaptor protein sqst-1/p62, suppressed the stress-induced locomotion and aldicarb sensitivity of the ALS/FUS mutant animals, but did not suppress the defects in basal autophagy defects (Baskoylu et al. 2022), suggesting that the autophagy defect, which leads to SQST-1/p62 accumulation is relevant for the severity of ALS.