OGG1 and cancer: Subsequentwork by the Helleday group showed that inhibiting hOGG1 by TH5487suppresses cancer cell growth, validating OGG1 as a potential anticancertarget,36 and mitigates pulmonary inflammationand lung fibrosis.38 It also sensitizescancer cells to radiation by high linear energy transfer protons.48 All these data confirmed hOGG1 as a promisingtarget for pharmaceutical intervention.