GSDMD and systemic lupus erythematosus: Previous studies have demonstrated that NLRP3 activation exacerbates inflammation and bone erosion in SLE‐associated rheumatoid arthritis [21], while pyroptosis‐associated factors, such as GSDMD, are highly expressed in renal tubules and peripheral blood mononuclear cells (PBMCs) of SLE patients and lung tissues of SLE‐PAH mice [22, 23, 24].