IL1B and Arthritis: Elevated serum IL‐1β levels have been closely linked to the severity of lupus‐associated arthritis, highlighting its pivotal role in inflammatory responses and tissue injury, while our latest findings suggest that the onset of SLE triggers excessive inflammation in the nucleus pulposus, a chondrocyte‐like tissue in the intervertebral disc, thereby facilitating the progression of intervertebral disc degeneration [17].