KEGG pathway enrichment analysis revealed that the anti-AD effects of the Kochiae Fructus phytochemicals could be associated with pathways in cancer, inflammatory mediator regulation of TRP channels, AGE-RAGE signaling pathway in diabetic complications, C-type lectin receptor signaling pathway, Th17 cell differentiation, EGFR tyrosine kinase inhibitor resistance, VEGF signaling pathway, lipid and atherosclerosis, T cell receptor signaling pathway, HIF-1 signaling pathway, and ErbB signaling pathway. This evidence concerns the gene EGFR and Alzheimer disease.