MAPK1 and Alzheimer disease: GO enrichment analysis showed that the ameliorative effects of Kochiae Fructus phytochemicals on AD might be attributed to multiple gene targets implicated in multiple BP, such as positive regulation of apoptotic response, inflammatory response, hormone-mediated signaling pathway, response to xenobiotic stimuli, positive regulation of transcription, DNA-templated, intracellular signaling pathway, positive regulation of ERK1, and ERK2 cascade, etc. Reports demonstrate that inflammation and apoptosis significantly contribute to the pathogenesis of AD.