A significant increase in the MDD vs. control groups was detected for IL-6 (MDD: 0.624 (2.262), controls: 0.338 (0.634); W = 1243, p = 0.032) and IL-10 (MDD: 0.0343 (0.0228), controls: 0.0288 (0.01500), p = 0.001, beta = 0.219, 95% CI: 0.0926 to 0.346). This evidence concerns the gene IL6 and major depressive disorder.