In our study, using the same TCGA CRC cohort (339 patients with available MSI status [ref. 35]), we found that low SOX9 expression (10 MSI-H CRCs out of 49 CRCs with low SOX9 expression) was not significantly associated with MSI-H (P = 0.2798, Fisher’s exact test). The gene discussed is SOX9; the disease is colorectal carcinoma.