DPEP1 is upregulated in CRC by query of both the colon adenocarcinoma (COAD) and rectal adenocarcinoma (READ) datasets from The Cancer Genome Atlas (TCGA) in comparison with normal adjacent tissue (Supplemental Figure 1, A and B; supplemental material available online with this article; https://doi.org/10.1172/jci.insight.186938DS1) (3, 29). This evidence concerns the gene DPEP1 and colon adenocarcinoma.