Notably, 5%–35% of clonally expanded T cells in BPH stroma-rich nodules expressed the CXCL13 receptor, CXCR5 (Supplemental Figure 2, M–Q), which was less frequently expressed in CD8+ T cells from BPH epithelial nodules (Supplemental Figure 2, R–V). This evidence concerns the gene CD8A and benign prostatic hyperplasia.