SLC16A7 and age-related macular degeneration: Interestingly, a genome-wide association study found that a splice variant of MCT3 (Slc16a8) was correlated with age-related macular degeneration (41), while another found AAV-mediated overexpression of MCT2 in retinal ganglion cells in a glaucoma mouse model resulted in increased cell survival and metabolic improvements (42).