Particularly, at validating specific European variants, Loesch et al. [32] found genome wide significance of rs356182 in SNCA, rs117615688 in CRHR1, rs1800547 and rs117615688 in MAPT loci in their LARGE-PD cohort; validating European GWAS reported by Nalls et al., 2019 [4]. The gene discussed is CRHR1; the disease is Parkinson disease.