Immune cells correlation results demonstrated significant differences in CD8 + T cells, macrophage, mast cells, plasmacytoid dendritic cell (pDC), T helper cells, T follicular helper cell (Tfh), T-helper 1 (Th1), T-helper 2 (Th2), tumor infiltrating lymphocyte (TIL), Treg cells in patients of high and low risk groups, and the infiltration of these immune cells was higher in the high-risk group (Fig. 4C). This evidence concerns the gene CD8A and neoplasm.