Gal-1 is also involved in regulating cell adhesion and migration by binding to integrins (such as α1β1, α5β1, α7β1, α2, α3, αv, and αIIbβ3) found in the plasma membrane of target cells (including trophoblasts and tumor cells) [54] and extracellular matrix (ECM) components like laminin and fibronectin [55]. This evidence concerns the gene GAL and neoplasm.