WFDC2 and ovarian carcinoma: Compared with the literature, commonly used clinical indicators for detecting asymptomatic ovarian cancer, such as CA125 and HE4, exhibit sensitivities no higher than 29% and 50% for stage I and II with specificity of 98%.[19] In our study, GMED models achieved a sensitivity of 75% and 100% for stage I and II ovarian cancer.