CA125, CA153, HE4, and CA199 showed significant contributions in identifying ovarian cancer when compared to the non‐cancer control group in the training set (CA125: p < 0.001; CA153: p < 0.001; HE4: p < 0.001; CA199: p = 0.002) (Figure 3E). This evidence concerns the gene WFDC2 and ovarian carcinoma.