On the basis of our research group's prior experience[12a] and previous studies,[15] we subsequently performed Western blot analyses to detect changes in the expression of several representative proteins associated with tumor proliferation (Cyclin E1, Cyclin D1, and PCNA) and metastasis (Vimentin, Snail, N‐cadherin, and E‐cadherin) (Figure S2J,K, Supporting Information), which further corroborated the effect of RNF112 on the proliferation and metastasis of BLCA cells. This evidence concerns the gene CCNE1 and neoplasm.