It is crucial to differentiate PHPT from the genetic disorder of familial hypocalciuric hypercalcemia (FHH), as biochemical tests, such as serum calcium, PTH, and phosphate levels often overlap, whereas management approaches differ significantly; the gold standard in the management of PHPT is surgery, in opposition to FHH, where PTX fails to lower calcium levels and generally is contraindicated (60). This evidence concerns the gene PTH and familial hypocalciuric hypercalcemia.