The objectives of the retrospective analysis were to evaluate the efficacy and safety of a preoperative single dose of intraperitoneal 5,000 units/kg erythropoietin plus a high dose of methylprednisolone against a high dose of methylprednisolone monotherapy in Chinese patients with spinal cord injuries due to traumatic head injuries who underwent decompression surgeries in a central coastal region of the People’s Republic of China. The gene discussed is EPO; the disease is spinal cord injury.