Moreover, both EPOR and RAG1, two genes upregulated by ETV6::RUNX1 and key factors in ETV6::RUNX1+ BCP‐ALL pathophysiology,6, 42, 55, 56 exhibited reduced levels upon H1‐0 knockdown (Figure S10B) as well as significant correlation with H1‐0 RNA expression in ETV6::RUNX1+ BCP‐ALL patient samples derived from the PeCan St. This evidence concerns the gene EPOR and acute lymphoblastic leukemia.