Immunosuppressive drugs such as oral corticosteroids, cyclosporine A, mycophenolate mofetil, and methotrexate may also be helpful, but their use is limited due to their side effects [11,12]. Dupilumab is a biologic agent used to treat adults with moderate to severe AD [13]. Janus kinase (JAK) inhibitors abrocitinib and upadacitinib also act by reducing proinflammatory cytokines through inhibition of the Janus kinase/signal transducer and activator of transcription (JAK-STAT) pathway and are approved for use in moderate to severe AD [14]. The gene discussed is SOAT1; the disease is Alzheimer disease.