Terminally differentiated CD8+ T cell %CD8+ T cell (p-value, 0.006; OR, 0.736; 95%CI, 0.591−0.916), CD25++ CD8+ T cell absolute count (p-value, 0.043; OR, 0.836; 95%CI, 0.702−0.995), and HLA DR on CD14+ CD16+ (p-value, 0.006; OR, 0.868; 95%CI, 0.783−0.961) decrease the risk of scoliosis. This evidence concerns the gene CD8A and scoliosis.