Studies on sepsis-induced lung injury, caused by cecal ligation puncture or lipopolysaccharide (LPS), have shown decreased expression levels of mitochondrial fusion proteins MFN2 and OPA1 in lung tissue, alveolar epithelial cells, and macrophages (Li Z. et al., 2023; Shi et al., 2019). The gene discussed is OPA1; the disease is Sepsis.