80 × 60 × 35 mm tumor with desmin (+), SMA (+), CD34 (-), CD117 (-), H-caldesmon (+), Ki-67 (+1%), SDHB (+), Dog-1 (-), and S-100 (-) immunohistochemistry indicative of leiomyoma confirmed after resection. The patient recovered well postoperatively with no complications. This evidence concerns the gene DES and leiomyoma.