PTENP1 and neoplasm: Sun et al. (2016) associated the increased expression of lncRNA FGFR3-AS1 with tumor growth, metastasis, and poor survival in osteosarcoma. The RNA molecule targeted the 3′ UTR of its antisense transcript, FGFR3, promoting its expression and downregulation of FGFR3-AS1 inhibited tumor proliferation in-vitro. LncRNA PTENP1 showed tumour-suppressive effects in gastric cancer by sponging miR-106b and miR-93, upregulating the expression of tumour inhibitor PTEN (Zhang et al., 2017).