Increased transcription levels of lncRNA NEAT1 can be associated with the proliferation, aggressiveness and angiogenesis of several cancer types such as gastric cancer, ovarian cancer and hepatoma carcinoma due to the crosstalk with the autophagic AKT/mTOR pathway, its ability to act as a competing endogenous RNA (ceRNA) to anti-angiogenic miRNA molecules like miR-17-5p, mir-127-5p and the subsequent enhancement of pro-angiogenic signalling such as TGF-β/Smad, VEGFs, FGFs and MMPs (Xu Y. et al., 2021; Yuan et al., 2021; Guo J. et al., 2022). The gene discussed is AKT1; the disease is cancer.