SOX6 and renal fibrosis: Knockdown of XIST also inhibited apoptosis and inflammation caused by renal fibrosis in mice model by mir-19b mediated downregulation of SOX6 (Xia et al., 2021), and several studies demonstrated XIST as a potential biomarker for diseases related to glomerular nephropathy (Huang et al., 2014; Ma et al., 2021) (Table 1).