In the context of inflammatory bowel diseases, lncRNA ANRIL, a 3.8K nucleotide-long antisense lncRNA present in the INK4 loci, demonstrated overexpression in ulcerative colitis and aggravated inflammation by negatively regulating miR-323b-5p, which itself is a negative regulator of TLR4/MyD88/NF-κβ pathway (Qiao et al., 2019) (Table 1). The gene discussed is TLR4; the disease is ulcerative colitis.