The association of lncRNAs with angiogenesis can be traced back to the crosstalk of the non-coding RNA molecules with cellular pathways associated with oncogenesis, including PI3K/AKT/mTOR, STAT3, NF-κβ, ERK/MEK, all of which are significantly bound to the expression of proangiogenic VEGFs and also associated with the vasculogenic mimicry and immunosuppressive characteristics of cancer cells (Zhao J. et al., 2019) (Table 4; Figure 3). This evidence concerns the gene AKT1 and cancer.