AGK was also considered to be a promoter of resistance to paclitaxel in nasopharyngeal carcinomas and this chemoresistance properties which eventually mediate tumor growth and metastasis is facilitated by overexpressed FOXM1 via JAK2/STAT3 signaling pathway (Zhao et al., 2021; Zhu Q. et al., 2020). This evidence concerns the gene STAT3 and nasopharyngeal carcinoma.