Although miR-107 was found to be downregulated in LSCC, but in the hypoxic microenvironment of breast and colon cancers, it was overexpressed where it inhibits VEGF-mediated angiogenesis via the downregulation of HIF-1β-mediated signaling pathway (Bao et al., 2012). This evidence concerns the gene ARNT and malignant colon neoplasm.