GFAP and Cognitive impairment: In a parallel investigation, Thongrong et al. (2023) determined that Pinostrobin (1) mitigated chronic stress-induced cognitive deficits and averted brain dysfunction by exhibiting anti-oxidant properties that diminished neuronal cell damage and bolstered the functionality of astrocyte markers, glial fibrillary acidic protein (GFAP), and excitatory amino acid transporter 2 (EAAT2).