MKI67 and neoplasm: Similar with the in vitro results, the analysis by xenograft tumor model suggested that CYT notably reduced the tumor size (Figure 7A) and growth curve (Figure 7B) of MDA-MB-231-DR cells, along with decreased level of KI-67 (Figure 7C), whereas overexpression of SRSF1 and MYO1B reversed these effects.