Among the commonly altered 35 ERVs, five out of the 14 differentially expressed ERVs shared by 16 days-post-implantation endometrial epithelium and IFNT treated endometrial epithelial cells located around an important interferon-induced gene, OAS1. And in nine differentially expressed ERVs in PPRV-infected tissues and cells, there were three located within OAS1. Though OAS1 activated in both embryo development and virus infection, the proximally activated ERVs are different, indicating specific physiological functions of distinct ERVs. The gene discussed is OAS1; the disease is viral infectious disease.