However, no significant multiplicative interactions were observed between C-index and AIP (HR = 0.91, 95% CI 0.78–1.05), Fatty liver (HR = 1.14, 95% CI 0.90–1.43), or HbA1c (HR = 1.05, 95% CI 0.94–1.16) in relation to incident diabetes risk. This evidence concerns the gene AIP and diabetes mellitus.