CRP and phenylketonuria: Recently, Giret et al. (2023) studied a cohort of early-treated PKU adult (n = 20, mean ± SD = 36,3 ± 8,5 years) with poor metabolic control (mean Phe ± SD = 1179 ± 550 μmol/L) compared to healthy matched control (n = 20) for several pro-inflammatory cytokines and CRP [40].