Two functionally important single-nucleotide polymorphisms (SNPs) have been identified in the CYP1A1 gene with regard to cancer susceptibility: a T to C base substitution in the 3′-UTR and an A to G transition resulting in a valine-to-isoleucine substitution at codon 462 (I462V) [10, 11]. Here, CYP1A1 is linked to cancer.