Except for the CuFeSe2-AMD3100-Gem + laser and CuFeSe2-AMD3100 + laser groups, the tumors in the other groups grew rapidly, demonstrating that neither laser irradiation alone nor CuFeSe2-AMD3100-Gem/CuFeSe2-AMD3100 exposure alone inhibited tumor growth (Fig. 9d). Here, GEM is linked to neoplasm.