Among the many differentially expressed genes identified, IL-24 expression was downregulated in TXNIP-KD versus WT MDA-MB-231 cells but upregulated in TXNIP-OE versus WT HCC-1954 cells (Supplementary Table 2), suggesting a positive association between TXNIP and IL-24 expression. The gene discussed is TXNIP; the disease is hepatocellular carcinoma.