BRCA2 and neurofibromatosis type 1: Loss of heterozygosity (LOH) of the wild type allele occurred in 5/13 patients (38%) with PGVs in genes ATM, BAP1, BRCA2, NBN and NF1. LOH in NF1, associated with tumors in neurofibromatosis type I, had not yet been reported in mesothelioma.