Based on the nodal degree, the following genes were identified as the top 10 central genes: DCN, CDH1, ERBB2, ERBB3, EGF, CBL, PIK3CA, EREG, GAB1, and HBEGF. These targets are hypothesized to be the primary targets in TQ ovarian cancer. The gene discussed is PIK3CA; the disease is ovarian cancer.