However, tumour‐bearing mice that received 3 weeks of chronic restraint stress (CRSTumor) displayed an average CD4+/CD8+ ratio of 2.4 ± 0.2, which was similar to control animals (1.8 ± 0.1) and to stressed mice in which tumours spontaneously regressed (2.1 ± 0.5; CRSRegress) (Figure 4C). Here, CD4 is linked to neoplasm.