Mutations in well‐known lung cancer–related genes (e.g., TP53, PTEN, PIK3CA, NF1, MSH2, MET, KRAS, EGFR, APC, ALK, MET, BRAF) were primarily identified as single‐nucleotide polymorphisms (SNPs) and insertions/deletions (InDels) (Figure 3A–F). The gene discussed is PIK3CA; the disease is lung cancer.