The stigma surrounding diabetes,31, 35, 36, 37, 41, 42, 43 insulin and injection24, 25, 28, 29, 36, 45 as well as medication taking in public27, 28, 31, 35, 36, 37, 38, 42 were major impediments to medication adherence. The gene discussed is INS; the disease is diabetes mellitus.