However, in the dataset obtained from our hospital, METTL3 and WTAP were poor prognostic factors for AML (Figure 2A,B), and multivariate Cox regression analysis showed that METTL3 was an independent prognostic factor (HR: 5.635, 95% CI: 1.147–27.694; p = 0.033) (Table 1). Here, WTAP is linked to acute myeloid leukemia.