Subsequently, we analyzed the information of newly diagnosed AML patients in the TCGA dataset, GEO database, and West China Hospital and found that PGC‐1α expression in newly diagnosed adults was significantly greater than that in NCs (p < 0.05) (Figure 7A–D) and decreased when AML patients reached CR (Figure 7E). Here, PPARGC1A is linked to acute myeloid leukemia.