As expected, these include clock genes such as Cry1 and Nfil3 (up) and Per3 and Nr1d2 (down) but also a few other genes, notably linked to retinal degeneration such as Myo7A61 that was substantially downregulated, or Loxl4 and Ppard that were highly upregulated. The gene discussed is PPARD; the disease is retinal degeneration.