Although loss or mutation of this gene in mice could not be phenotypically correlated with retinal degeneration,61, 85 it is tempting to speculate that in the context of P23H Rho, suboptimal transport of outer segment constituents due to the absence of Myosin VIIa might further weaken photoreceptor structure and precipitate their death. Here, MYO7A is linked to retinal degeneration.