Dyspnea (N = 3), hypertension (N = 1), tachycardia (N = 2), lack of appetite (N = 2), arthralgia (N = 1), and flush (N = 1) were reported exclusively in IL-2 patients, whereas headache (N = 3), abdominal pain (N = 4), diarrhea (N = 2), sleep disorder (N = 1), and herpes labialis (N = 2) were reported exclusively in T-VEC patients. Here, IL2 is linked to herpes labialis.