Our ETP-ALL patients were enriched in myeloid-associated mutations such as FLT3, NRAS, WT1, U2AF1 and TP53, with relatively reduced frequency of gene mutations typically seen in other subtypes of T-ALL, such as NOTCH1, FBXW7 and JAK3, similar to the findings of Ye et al [13]. This evidence concerns the gene FBXW7 and acute lymphoblastic leukemia.