Second, tumor subsets enriched for microenvironment features, including hypoxia markers (e.g., Slc2a1, Pdk1, Car9), extracellular matrix (ECM) genes (e.g., Matn2, Fn1, Dcn, Col6a1), vasculature (e.g., Cdh5, Pecam1, Vwf), and interferon response genes (e.g., Rsad2, Ifit3, Gbp3, Cxcl10, Cd274). The gene discussed is SLC2A1; the disease is neoplasm.