IL-6 becomes detectable within 1 h after triggering an infectious stimulus, reaches its plateau in 4 to 6 h, and the IL-6 release may be essentially abolished by 36 h, even while the infection remains unchallenged; as IL-6 blood level drops, acute phase reactants (such as CRP) increase (Perenyi et al., 1999). This evidence concerns the gene CRP and infection.