Laboratory studies showed leukocytosis with a white blood cell count of 22.9 × 103/μl, neutrophils at 88%, and elevated liver function tests: SGPT (ALT) at 483 U/l, SGOT (AST) at 384 U/l, alkaline phosphatase at 198 U/L, and bilirubin at 2.8 mg/dl. The gene discussed is GOT1; the disease is Increased total leukocyte count.