CHCHD10 and Parkinson disease: The phenotypic complexity seen in carriers of CHCHD10 variants were similar to that of C9orf72. Initially identified in ALS-FTD, C9orf72 has since been associated with a wide range of neurodegenerative and psychiatric conditions, including Alzheimer's, Parkinson's, Huntington-like phenotypes, and schizophrenia (11).