SLC5A2 and chronic kidney disease: Currently, medications for CKD and RF include ACEIs and ARBs (e.g., lisinopril, losartan, valsartan), diuretics (e.g., hydrochlorothiazide), and SGLT2 inhibitors (e.g., empagliflozin) (Momoniat et al., 2019; Johnson and Spurney, 2015).